Chinese researchers have discovered a new approach to cancer by utilizing a plasma treatment to induce apoptosis(the death of cancer cells)without any noticeable side effects on normal cells.
The catch is that while a plasma-activated medium (PAM) can be dealt with as a drug, there is often a dose-effect relationship. And within the plasma community, several researchers analyze the plasma dose as either the plasma therapy time or the power put into the plasma per surface.
In Physics of Plasmas, the scientists’ description of a plasma dose is equal to total oxidation potential (ETOP). It can be used for PAM to disclose the plasma dose-response connection for several cell types. ETOP is established on the oxidation ability of reactive oxygen and nitrogen species.
Plasma treatment time and the power put into plasma per surface “are not the right choices to define the plasma dose,” explained Xinpei Lu, Huazhong University of Science and Technology. “The essential part of the plasma treatment is the reactive species delivered to PAM. The definition of the plasma dose we present is based on this reactive species concentration.”
The objective of plasma medicine is to manipulate a differentiated interaction of specific plasma components through certain elements or functionalities of living cells to regulate and, ideally, normalize therapeutic impacts. One critical limitation on the path from the laboratory bench to the bedside is the dose-response connections of plasma on biological subjects.
